Tuesday, May 16, 2017

What is an embryo transfer?


"The patient returns to the clinic to have the embryos transferred. Anesthesia is often not necessary, although a sedative may be used. An ultrasoundmay be used to help guide the physician as he transfers the embryos. A predetermined number of embryos are loaded into a fine transfer catheter that passes through the vagina and cervix, into the uterus.
The embryos are deposited from the catheter into the uterus. Following this procedure, the patient usually remains in a recovery room resting on her back and is discharged 4-6 hours after the procedure. The couple will then wait and optimistically watch for early pregnancy symptoms."
www.americanpregnancy.org

Saturday, May 13, 2017

#1 IVF update on our embryos

  Yesterday they were able to retrieve 8 eggs. Today they reported that only 7 fertilized because one egg wasnt mature enough to fertilize. But 7 out of 8 is a great number!
  We offically have 7 embryos! Because our fertlization report came back so good and they don't appear to be struggling they are waiting to transfer on day 5. By waiting until day 5 they will be able to weed out the weakest embryo's because they will start falling off. The surviving embryos will be examined and they will transfer one and freeze whats left (if by day 5 there is some left). They will not be checked on from now until transfer day. On Wednesday they will call us if something horrible happens but if not we will be in Rockford on Wednesday at 1:40 to place our embaby back home.


Trmbaby.com

"The laboratory is a critical part of the IVF process. The eggs that are harvested are placed into dishes where they will be counted and evaluated.
Approximately six hours after egg retrieval, fertilization is accomplished by placing a small concentration of sperm onto each egg, or by ICSI (where a single sperm is injected into an egg.) Approximately 18 hours after retrieval (the day after egg retrieval) we will evaluate fertilization of the eggs.
Fertilized eggs (zygotes) have two pronuclei. One pronucleus is a packet containing half of the female’s DNA. The other pronucleus contains half of the male’s DNA. This genetic material will unite to form the full complement of genetic material that will make an embryo.
The embryos are cultured (or grown) in incubators with an environment designed to mimic the human fallopian tube. A careful balance of carbon dioxide, oxygen, and nutrients are maintained at the correct pH (acid content) to promote embryo growth.
Embryos destined to result in pregnancy will progress through several well-defined stages including zygote, cleavage and blastocyst stages. Only normally fertilized eggs are kept in culture. Not all embryos will grow in culture. Some of them will be genetically abnormal, while others cease to grow for unknown reasons.
Cleavage-stage embryos are those that are dividing into progressively smaller cells. Two days after fertilization, normal embryos are between two and six cells. Three days after fertilization, most normal embryos are between seven and nine cells.
Four days after fertilization, most normal embryos have reached the morula stage (too many cells to reliably count with a microscope).
Blastocysts are embryos that are nearly ready to implant. Blastocysts have developed three distinct regions:
    • An inner cell mass, which becomes the baby
    • The trophectoderm, which becomes the placenta
    • The fluid-filled cavity, which will form a structure called the yolk sac

Embryo transfer

Your physician and embryologist will determine the ideal day for your embryo transfer.
The very best embryos will be selected for embryo transfer. The number of embryos transferred will depend on several factors, including your preference, the quality of the embryos and the ASRM Embryo Transfer Guidelines.
If you have other embryos that are suitable for freezing, they can be frozen (cryopreserved).
It is critical to understand that morphology scoring of the embryos does not evaluate the genetic potential of the embryo (e.g., will the baby have a normal number of chromosomes) or the potential health of a baby that grows from the embryo.
While pre-implantation genetic testing can investigate the chromosome number of the embryo, no test can guarantee a healthy baby after IVF."

Friday, May 12, 2017

What is a Egg retrieval?

What are they doing today??

Egg retrieval

Egg retrieval can be done in your doctor's office or a clinic 34 to 36 hours after the final injection and before ovulation.
  • During egg retrieval, you'll be sedated and given pain medication.
  • Transvaginal ultrasound aspiration is the usual retrieval method. An ultrasound probe is inserted into your vagina to identify follicles. Then a thin needle is inserted into an ultrasound guide to go through the vagina and into the follicles to retrieve the eggs.
  • If your ovaries aren't accessible through transvaginal ultrasound, an abdominal surgery or laparoscopy — a procedure in which a tiny incision is made near your navel and a slender viewing instrument (laparoscope) is inserted — may be used to guide the needle.
  • The eggs are removed from the follicles through a needle connected to a suction device. Multiple eggs can be removed in about 20 minutes.
  • After egg retrieval, you may experience cramping and feelings of fullness or pressure.
  • Mature eggs are placed in a nutritive liquid (culture medium) and incubated. Eggs that appear healthy and mature will be mixed with sperm to attempt to create embryos. However, not all eggs may be successfully fertilized.
After they retrieve my eggs they will attempt to fertilize them:

Fertilization

Fertilization can be attempted using two common methods:
  • Insemination. During insemination, healthy sperm and mature eggs are mixed and incubated overnight.
  • Intracytoplasmic sperm injection (ICSI). In ICSI, a single healthy sperm is injected directly into each mature egg. ICSI is often used when semen quality or number is a problem or if fertilization attempts during prior IVF cycles failed.
In 1-2 days we will get the fertilization report and find out if they are transfering our embryo on Monday or Wednesday. Fingers crossed we get several eggs and after fertilization we have enough to freeze after transfering one (or two). 


www.mayoclinic.com 




Wednesday, May 10, 2017

#1 IVF 4th Scan

  Today I got my final ultrasound of my ovaries for my upcoming IVF procedure. I lost count of the follicles he was counting but I believe they are all still there. I was scared of them somehow disappearing. They are big though! The smallest was a 17mm and the largest was a 25mm. This worries me because I still have a couple days until my retrieval and they could continue to grow.

 I asked him if there was a such thing as too big and he told me "uhhh not really. We like to see them between 18mm-20mm." but personally I've heard stories of eggs not fertilizing because they were too mature. He told me that everything looks good so I'm just going to take his word for it.

The plan is to trigger ovulation tonight at 10:45 PM and my egg retrieval is scheduled for Friday at 9:45 AM. I am looking forward to it! I'm in so much pain from all the activity in my ovaries... I will update after we gather our eggs and let you know how many they were able to get!




Monday, May 8, 2017

IVF #1 third scan

  At my last scan I had 6 follicles today I have 15! They are all sizes 11-19mm. Thats potentially 15 eggs we could retrieve! Thats great news! The doc made me a little nervous because he called the IVF nurse and told her I may be "growing too fast" but I'm trying not to worry. Its hard for me to stay positive and not stress over every detail. I have my last scan in a couple of days and we head to Rockford Thursday night!

Symptoms: I am in pain when I move wrong one way or the other. I have little appetite and feel like I am carrying around 15 bowling balls.




Friday, May 5, 2017

IVF #1 second scan

  I went and saw my doctor today and so far I have been stimulating my ovaries for 6 days and my left ovary has 6 follicles between the sizes of 11mm and 13mm. My right side has several small ones but they were to small to measure. I am on a shot to help keep me from ovulating those 6 follicles when they reach maturity (about 18-20mm).
  I asked the doctor if this is where I should be at this point and he said my left side is doing well but my right needs more time to grow. He said he is optimistic and I have plenty of time. Fingers crossed those babies grow! (Hehe babies) .









Wednesday, May 3, 2017

IVF #1 first scan

I don't really have any updates. My ovaries have follicles and doc didn't say anything was wrong. This doc doesn't give me much feedback and I was too nervous to ask questions. I believe there are less then 10 all together but I will know more Friday.


Can you spot my follicles?

 This is just the ultrasound machine